Senator Melecio Arranz was born on May 24, 1888 in Vigan, Ilocos Sur. He obtained his degree of Bachelor of Science in Civil Engineering from the University of Sto. Tomas.
His government service began in 1914 when he worked as Junior Assistant Engineer at the Bureau of Public Works and became District Engineer of Bataan and Rizal (1919) and later was promoted as Supervising District Engineer.
As Senator, he was elected in 1927 representing the First Senatorial District comprising of Cagayan, Isabela, Ilocos Sur, Ilocos Norte and Abra. Reelected in 1934, 1941 and 1946, his term ended in 1971. He was floor leader and Chairman of the Committee on Public Works and Communications (1936) and floor leader and Senate President Pro-Tempore (1946-1949).
In 1947, he was appointed Chief Delegate of the Philippines to the United Nations Commission on Korea.
He was married to Consuelo Arguelles. He died on April 24, 1966.